As KM already pointed out, the patch will work wherever WinMx itself works.
On linux winmx works well with older WINE versions (up to 0.9.16, in later versions they made some changes that haven't been fixed to work with winmx yet).
WINE has been ported to MacOs, that project is called DARWINE and is almost current in versions.
I'm not sure about which versions of that will work with winmx though, i.e. if there's the same problem with the latest versions.
If someone has any informations on this please post

PS: you can get WINE here:
http://www.winehq.comand DarWINE is here:
http://sourceforge.net/projects/darwine/